We are seeking an EXperienced
immunoassay development scientist
We are currently seeking an experienced scientist in immunoassay development and validation to join our biomarkers and diagnostic development team . You will participate in projects aimed at the development and validation of novel assays aimed at detection and quantification of protein biomarkers associated with neurodegenerative diseases. An important focus will be the development of assays that enable sensitive and accurate quantification of multiple disease-associated forms of alpha-Synuclein.
Responsibilities
- Execute different types of immunoassays for accurate and sensitive detection and quantification of protein biomarkers in human tissues and biological fluids under minimal supervision.
- Use different immunoassay platforms to conduct biomarker discovery and validation studies.
- Be familiar with the technical validation of assays, such as limit of detection, specificity, sensitivity, reproducibility, and other analytical parameters.
- Perform routine laboratory experiments, including designing experiments and analysis of data.
- Be familiar with the most common molecular biology and biochemical techniques.
- Organize and compile data, and present reports on results at internal meetings.
- Consult and keep up with the scientific literature in the relevant field.
- Maintain, clear, complete and up-to-date lab notebook and documentation of all experiments, results and reports.
- Understand and adhere to corporate standards regarding code of conduct, safety, and compliance with international standards adopted by ND Biosciences.
- Be in charge of ordering and stocking of material/reagents for immunoassay establishment.
Qualifications
- MSc or PhD in Biological Sciences or a related discipline with at least 3 years of demonstrated experience in the development, optimization, validation, and execution of immunoassays for biomarker discovery.
- Strong understanding of protein biochemistry, biochemical concepts and immunoassays and biochemical assays.
- Knowledge and expertise in the use and application of different immunoassay platforms for biomarker discovery and validation and diagnostic purposes (ELISA).
- Experience in handling and processing of human tissues and biological fluids for biomarker discovery.
- Knowledge and experience in protein post-translational modifications, misfolding and aggregation or neurodegenerative diseases is a plus.
- Proven ability to execute and interpret critical experiments independently.
- Proven problem-solving and time-management skills.
- Good written and oral communication skills in English.
- Strong interpersonal skills and ability to work in a collaborative environment and to be an effective team player.
- Strong organizational skills and ability to multitask and work within timelines.
- Industry experience is preferable.
- Being eligible to work in Switzerland is a plus.
Reporting
The successful candidate will report to the Head of Biomarkers and Diagnostic Development, Dr. Lara Petricca.
Application
To apply for this position, please send an email with your CV and cover letter to: lpetricca@nd-biosciences.com
If your qualifications meet the requirements of the position, you will be contacted to set up a video-call or in-person interview.
About ND Biosciences
ND Biosciences is a biotechnology company that was founded to develop novel therapeutics and biomarkers for neurodegenerative diseases.
The therapies developed at ND Biosciences focus on treating both early and late stages of neurodegenerative diseases. This is accomplished by developing combination therapies that can prevent the initiation of protein aggregation in the first place, and that neutralize the activities of existing aggregates
ND Biosciences has developed integrated proprietary platforms that enable transformative drug discovery and preclinical development programs. These platforms are based on unique capabilities and model systems that allow ND Biosciences to:
- Reverse-engineer the complexity of ND protein pathologies under controlled conditions
- Reproduce key processes underlying pathology formation and neurodegeneration in living neurons
- Develop novel companion diagnostic assays and imaging agents that capture the diversity and complexity of protein pathology in the brain